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Mini simpozij infrastrukturnih centrov

Mini simpozij infrastrukturnih centrov Medicinske fakultete Univerze v Ljubljani, bo potekal 21. junija 2018 med 14:00 in 17:00 v srednji predavalnici na Medicinski fakulteti Univerze v Ljubljani na Korytkovi 2.

Taste of Genomics

Taste of Genomics: the 70th anniversary of Prof. Radovan Komel and 13th CFGBC Scientific Symposium will take place from June 20th-21st 2018 at the University of Ljubljana, Faculty of Medicine, Slovenia.

Systems Medicine Conference in Slovenia

Systems Medicine Conference in Slovenia: National Awareness Event,12th CFGBC Symposium and “Systems Medicine” Workshop took place from June 8th-9th 2017 at Hotel Slon, Ljubljana, Slovenia.

2009-04-15
CFGBC: Core publications

Core publications

  1. Režen T, Juvan P, Fon Tacer K, Kuzman D, Roth A, Pompon D, Aggerbeck LP, Meyer UA, Rozman D (2008) The Sterolgene v0 cDNA microarray: a systemic approach to studies of cholesterol homeostasis and drug metabolism. BMC Genomics 9:76.
    link, pdf
  2. Korošec T, Ačimovič J, Seliškar M, Kocjan D, Tacer KF, Rozman D, Urleb U (2008) Novel cholesterol biosynthesis inhibitors targeting human lanosterol 14α-demethylase (CYP51). Bioorg Med Chem 16(1):209-21.
    link
  3. Režen T, Contreras JA, Rozman D (2007) Functional genomics approaches to studies of the cytochrome p450 superfamily. Drug Metab Rev 39(2-3):389-99.
    link, preprint pdf
  4. Fon Tacer K, Kuzman D, Seliškar M, Pompon D, Rozman D (2007) TNF-α interferes with lipid homeostasis and activates acute and proatherogenic processes. Physiol Genomics 31(2):216-27.
    link, preprint pdf, supplement pdf
  5. Lepesheva GI, Seliškar M, Knutson CG, Stourman NV, Rozman D, Waterman MR (2007) Conformational dynamics in the F/G segment of CYP51 from Mycobacterium tuberculosis monitored by FRET. Arch Biochem Biophys 464(2):221-7.
    link
  6. Seliškar M, Rozman D (2006) Mammalian cytochromes P450 - Importance of tissue specificity. Biochim Biophys Acta 1770(3):458-66.
    link, preprint pdf
  7. Fink M, Ačimovič J, Režen T, Tanšek N, Rozman D (2005) Cholesterogenic lanosterol 14α-demethylase (CYP51) is an immediate early response gene. Endocrinology 146(12):5321-31.
    link, preprint pdf
  8. Van Driessche N, Demšar J, Booth EO, Hill P, Juvan P, Zupan B, Kuspa A, Shaulsky G (2005) Epistasis analysis with global transcriptional phenotypes. Nat Genet 37(5):471-7.
    link
  9. Juvan P, Demšar J, Shaulsky G, Zupan B (2005) GenePath : from mutations to genetic networks and back. Nucleic Acids Res 33:749-52.
    link
  10. Cotman M, Ježek D, Fon Tacer K, Frangez R, Rozman D (2004) A functional cytochrome P450 lanosterol 14α-demethylase CYP51 enzyme in the acrosome: transport through the Golgi and synthesis of meiosis-activating sterols. Endocrinology 145(3):1419-26.
    link
  11. Zupan B, Demšar J, Bratko I, Juvan P, Halter JA, Kuspa A, Shaulsky G (2003) GenePath : a system for automated construction of genetic networks from mutant data. Bioinformatics 19(3):383-9.
    link
  12. Zupan B, Bratko I, Demšar J, Juvan P, Curk T, Borštnik U, Beck JR, Halter J, Kuspa A, Shaulsky G (2003) GenePath : a system for inference of genetic networks and proposal of genetic experiments. Artif Intell Med 29:107-30.
    preprint pdf
  13. Halder SK, Fink M, Waterman MR, Rozman D (2002) A cAMP-responsive element binding site is essential for sterol regulation of the human lanosterol 14α-demethylase gene (CYP51). Mol Endocrinol 16(8):1853-63.
    link, preprint pdf
  14. Debeljak N, Horvat S, Vouk K, Lee M, Rozman D (2000) Characterization of the mouse lanosterol 14α-demethylase (CYP51), a new member of the evolutionarily most conserved cytochrome P450 family. Arch Biochem Biophys 379(1):37-45.
    link
  15. Rozman D, Fink M, Fimia GM, Sassone-Corsi P, Waterman MR (1999) Cyclic adenosine 3',5'-monophosphate(cAMP)/cAMP-responsive element modulator (CREM)-dependent regulation of cholesterogenic lanosterol 14α-demethylase (CYP51) in spermatids. Mol Endocrinol 13(11):1951-62.
    link
  16. Rozman D, Strömstedt M, Tsui LC, Scherer SW, Waterman MR (1996) Structure and mapping of the human lanosterol 14α-demethylase gene (CYP51) encoding the cytochrome P450 involved in cholesterol biosynthesis; comparison of exon/intron organization with other mammalian and fungal CYP genes. Genomics 38(3):371-81.
    link
  17. Strömstedt M, Rozman D, Waterman MR (1996) The ubiquitously expressed human CYP51 encodes lanosterol 14α-demethylase, a cytochrome P450 whose expression is regulated by oxysterols. Arch Biochem Biophys 329(1):73-81.
    link
2006 - University of Ljubljana, Faculty of Medicine, Center for Functional Genomics and Bio-chips.