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Slides from Steroid Biochemistry 2008 course (undergraduate studies of Medicine and Dental Medicine, Faculty of Medicine University of Ljubljana): first, second and third lecture.

Slides from Functional Genomics course: first, second and third lecture.

Slides from DNA-protein interactions – experimental approaches (graduate course of Genetics and Biotechnology, Biotechnical Faculty, University of Ljubljana): DPI-1a-2008-BF.pdf, DPI-2-2008-BF.pdf, DPI-3-2008-BF.pdf.

2009-11-27
Damjana Rozman's Publications

Important publications last 3 years

Here is list of my core publications for the last 3 years. For exhaustive list see my bibliography from COBISS.

  • Budefeld T, Jezek D, Rozman D, Majdic G (2009) Initiation of steroidogenesis precedes expression of cholesterologenic enzymes in the fetal mouse testes. Anat Histol Embryol 38(6):461-6.
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  • Tamasi V, Juvan P, Beer M, Rozman D, Meyer UA (2009) Transcriptional activation of PPARalpha by phenobarbital in the absence of CAR and PXR. Mol Pharm 6(5):1573-81.
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  • Rezen T, Tamasi V, Lovgren-Sandblom A, Bjorkhem I, Meyer UA, Rozman D (2009) Effect of CAR activation on selected metabolic pathways in normal and hyperlipidemic mouse livers. BMC Genomics 10:384.
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  • Acimovic J, Lovgren-Sandblom A, Monostory K, Rozman D, Golicnik M, Lutjohann D, Bjorkhem I (2009) Combined gas chromatographic/mass spectrometric analysis of cholesterol precursors and plant sterols in cultured cells. J Chromatogr B Analyt Technol Biomed Life Sci 877(22):2081-6.
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  • Monostory K, Pascussi JM, Szabo P, Temesvari M, Kohalmy K, Acimovic J, Kocjan D, Kuzman D, Wilzewski B, Bernhardt R, Kobori L, Rozman D (2009) Drug interaction potential of 2-((3,4-dichlorophenethyl)(propyl)amino)-1-(pyridin-3-yl)ethanol (LK-935), the novel nonstatin-type cholesterol-lowering agent. Drug Metab Dispos 37(2):375-85.
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  • Acimovic J, Fink M, Pompon D, Bjorkhem I, Hirayama J, Sassone-Corsi P, Golicnik M, Rozman D (2008) CREM modulates the circadian expression of CYP51, HMGCR and cholesterogenesis in the liver. Biochem Biophys Res Commun 376(1):206-10.
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  • Podobnik B, Stojan J, Lah L, Krasevec N, Seliskar M, Rizner TL, Rozman D, Komel R (2008) CYP53A15 of Cochliobolus lunatus, a target for natural antifungal compounds. J Med Chem 51(12):3480-6.
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  • Seliskar M, Kosir R, Rozman D (2008) Expression of microsomal lanosterol 14alpha-demethylase (CYP51) in an engineered soluble monomeric form. Biochem Biophys Res Commun 371(4):855-9.
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  • Rezen T, Juvan P, Fon Tacer K, Kuzman D, Roth A, Pompon D, Aggerbeck LP, Meyer UA, Rozman D (2008) The Sterolgene v0 cDNA microarray: a systemic approach to studies of cholesterol homeostasis and drug metabolism. BMC Genomics 9:76.
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  • Korosec T, Acimovic J, Seliskar M, Kocjan D, Tacer KF, Rozman D, Urleb U (2008) Novel cholesterol biosynthesis inhibitors targeting human lanosterol 14alpha-demethylase (CYP51). Bioorg Med Chem 16(1):209-21.
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  • Rezen T, Contreras JA, Rozman D (2007) Functional genomics approaches to studies of the cytochrome p450 superfamily. Drug Metab Rev 39(2-3):389-99.
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  • Kohalmy K, Tamasi V, Kobori L, Sarvary E, Pascussi JM, Porrogi P, Rozman D, Prough RA, Meyer UA, Monostory K (2007) Dehydroepiandrosterone induces human CYP2B6 through the constitutive androstane receptor. Drug Metab Dispos 35(9):1495-501.
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  • Lepesheva GI, Seliskar M, Knutson CG, Stourman NV, Rozman D, Waterman MR (2007) Conformational dynamics in the F/G segment of CYP51 from Mycobacterium tuberculosis monitored by FRET. Arch Biochem Biophys 464(2):221-7.
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  • Fon Tacer K, Kuzman D, Seliskar M, Pompon D, Rozman D (2007) TNF-alpha interferes with lipid homeostasis and activates acute and proatherogenic processes. Physiol Genomics 31(2):216-27.
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  • Seliskar M, Rozman D (2007) Mammalian cytochromes P450--importance of tissue specificity. Biochim Biophys Acta 1770(3):458-66.
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2006 - University of Ljubljana, Faculty of Medicine, Center for Functional Genomics and Bio-chips.